Hypochlorous acid and taurine-N-monochloramine in periodontal diseases.
Mainnemare, A., Mégarbane, B., Soueidan, A., Daniel, A., & Chapple, I. L. C. (2004). Hypochlorous acid and taurine-N-monochloramine in periodontal diseases. Journal of dental research, 83(11), 823-831.
In addition to their anti-infectious properties, the end-products of the PMN respiratory-burst, HOCl and TauCl, possess, at low concentrations, very interesting and complementary activities which modulate crucial phases of the inflammatory process, cell turnover and periodontal tissue healing. Such activities may be summarized as follows: (1) neutralization of antigens and pathogenic agents following chlorination and/or their oxidation; (2) direct neutralization of metalloproteinases, IL-5 and IL-6; (3) enhancement of inflammatory mediator binding to 2-macroglobulins; and (4) reduction of the binding of growth factors to 2-macroglobulins.
References
Mainnemare, A., Mégarbane, B., Soueidan, A., Daniel, A., & Chapple, I. L. C. (2004). Hypochlorous acid and taurine-N-monochloramine in periodontal diseases. Journal of dental research, 83(11), 823-831.
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