Del Rosso, J. Q., & Bhatia, N. (2018). Status report on topical hypochlorous acid: clinical relevance of specific formulations, potential modes of action, and study outcomes. The Journal of Clinical and Aesthetic Dermatology, 11(11), 36.
Topical formulations of stabilized, pH-neutral HOCl (e.g., solution, gel, spray) have been evaluated in several studies demonstrating both antimicrobial effects and therapeutic benefit in many cutaneous disorders, including seborrheic dermatitis, atopic dermatitis-associated pruritus, acne vulgaris, diabetic foot ulcers, and hypertrophic scars/keloids. Topical HOCl appears to be well tolerated and safe, without any major adverse events reported.