Advanced care for acute and chronic wounds
BIHOCL PureCleanse is a scientifically formulated easy-to-use antimicrobial solution, designed for the advanced treatment of chronic and acute wounds.
Safe, Effective, Thoughtfully Designed Solutions
Treating chronic wounds and burns can be extremely challenging. Now with care plans utilizing the principles of wound bed preparation and T.I.M.E.1,2,3 clinicians are using hypochlorous acid, antimicrobial solutions to effectively reduce chronic wound bed bioburden4,5. In fact, white blood cells produce hypochlorous acid on demand as a first line of natural defense against infection and triggers a cascade of changes that are hallmarks of healing and tissue repair.
With no contraindications for use, hypochlorous acid solutions do not damage healthy cells and tissue as they cleanse and debride the wound bed in preparation for healing 7,8,9,10. As a pure hypochlorous solution, BIHOCL PureCleanse is indicated for the treatment of stage I-IV pressure ulcers, venous insufficiency ulcers, diabetic ulcers, post-surgical wounds, first and second degree burns and minor abrasions6.
BIHOCL
PureCleanse
A safe and non-cytotoxic, yet powerful antimicrobial cleansing solution for wounds, skin, and burns.
BIHOCL
PureCleanse Plus Irrigation Kits
Our cleansing solution for the enhanced care of wounds that need it most. Pure HOCl at a higher concentration and lower pH than our standard PureCleanse solution. Safe for use on all wounds. Currently available in kit format.
BIHOCL
Innovative Delivery Devices
Sterile attachments designed to efficiently and effectively cleanse and debride wounds and remove biofilm at an optimized pressure.
The Shield provides superior backsplash prevention and optimal pressure while the Probe provides easy debridement and cleansing access into deep tunnelling wounds.
Powerful Antimicrobial
BIHOCL hypochlorous technology is based on the body’s innate cellular response to infection. BIHOCL PureCleanse is a broad spectrum antiseptic which is highly effective against a wide range of microorganisms including gram negative and positive bacteria, antibiotic resistant strains, viruses, fungi, yeasts, and prions6.
Groundbreaking Safety
BIHOCL PureCleanse is non-cytotoxic, non-mutagenic, hypoallergenic, non-pyrogenic, endotoxin free and does not require rinsing6. Our pure and stable hypochlorous acid formulation strikes a unique balance between a powerful antimicrobial and the gentleness of saline.
Simple, Innovative Application
BIHOCL PureCleanse has been designed with healthcare providers and patients in mind. Our easy-to-use irrigation attachments, optimized for solution delivery, provide effective wound bed debridement6.
Biofilm Disruption
Over 90% of chronic wounds contain bacteria and fungi living within a biofilm construct¹¹ and create many challenges in wound care. Ample research has shown that hypochlorous acid solutions such as BIHOCL PureCleanse are effective in disrupting and dismantling complex biofilms through the combined effect of its unique biochemistry and mechanical, pressurized delivery1,13.
Odour Control
The odour associated with non-healing chronic wounds is the result of the microbial breakdown of molecules released in tissue and cellular debris. Hypochlorous acid has been shown to dismantle many of these odour-causing compounds, decreasing VOC output and improving the patient’s quality of life5,14.
BIHOCL PureCleanse
Product Overview
Everything you need to know — at a glance.
Available in English and French.
BIHOCL PureCleanse
Instructions for Use
Easy-to-follow instructions that are applicable to a wide variety of clinical applications using our unique delivery devices.
Available in English and French.
BIHOCL PureCleanse
Order Sheet
A list of commonly available product variations with key information.
BIHOCL PureCleanse Plus irrigation kits for fast, safe, and effective wound cleansing.
Designed for clinicians and NSWOCs to effectively apply BIHOCL PureCleanse at the optimal PSI to cleanse the wound.
Hospitals
Home Care
Long Term Care
Out Patient
“Hypochlorous acid use has an important but under recognized place in the armamentarium that clinicians treating patients with wounds can draw upon, and do so with the assurance that well-characterised, potent and effective products are available⁵”
Prof. Keith Harding
“Hypochlorous acid use has an important but under recognized place in the armamentarium that clinicians treating patients with wounds can draw upon, and do so with the assurance that well-characterised, potent and effective products are available⁵”
Prof. Keith Harding
“Hypochlorous acid use has an important but under recognized place in the armamentarium that clinicians treating patients with wounds can draw upon, and do so with the assurance that well-characterised, potent and effective products are available⁵”
Prof. Keith Harding
Frequently Asked Questions
What is BIHOCL PureCleanse and what is it used for?
BIHOCL PureCleanse is an antimicrobial wound cleanser that contains only two elements: electrolyzed saline and pure hypochlorous acid (HOCl) as the active ingredient. It is designed for use by wound care specialists, nurses, doctors, and surgeons to clean wounds and promote healing, and also by their patients in an at-home care environment.
How does BIHOCL PureCleanse work?
HOCl is a naturally occurring molecule produced by our bodies’ white blood cells to fight infections. In BIHOCL PureCleanse, our pure formulation HOCl acts as a disinfectant; killing bacteria and other pathogens while also helping to remove debris from the wound through use of our innovative delivery systems.
What types of wounds can BIHOCL PureCleanse be used on?
BIHOCL PureCleanse can be used on a variety of wounds, including surgical incisions, pressure ulcers, diabetic ulcers, and burns. It is also suitable for use on infected or contaminated wounds.
What is the formulation (concentration, pH, etc.) of BIHOCL PureCleanse?
Our advanced wound cleanser is available in two formulations, each of which feature a variety of applicators and sizes.
- BIHOCL PureCleanse
330 ppm, 5.5 pH - BIHOCL PureCleanse Plus
500 ppm, 4.4 pH
How should BIHOCL PureCleanse be applied to a wound?
First, thoroughly clean the affected area with the BIHOCL PureCleanse solution. Apply the product directly to the wound using a sterile cotton swab or gauze. If necessary, gently remove any debris or necrotic tissue from the wound with a sterile instrument. Rinse the wound thoroughly with the solution. Allow the wound to air-dry or cover with a sterile dressing.
How often should BIHOCL PureCleanse be applied?
The frequency of application will depend on the specific wound and its severity. It is recommended to follow the instructions of the wound care specialist, nurse, doctor, or surgeon who is treating the wound.
Is BIHOCL PureCleanse safe to use on all patients?
BIHOCL PureCleanse is generally considered safe for use on all patients. However, as with any wound care product, it is important to follow the instructions of the wound care specialist, nurse, doctor, or surgeon who is treating the wound and to check for any potential allergies or sensitivities.
Can BIHOCL PureCleanse be used in conjunction with other wound care products?
Yes, BIHOCL PureCleanse can be used in conjunction with other wound care products such as dressings and topical antibiotics. It is recommended to follow the instructions of the wound care specialist, nurse, doctor, or surgeon who is treating the wound and to avoid using products that may interfere with the healing process.
How should BIHOCL PureCleanse be stored?
BIHOCL PureCleanse should be stored at room temperature and protected from light and heat. Keep the product out of reach of children and pets.
What precautions should be taken before using BIHOCL PureCleanse?
Pure HOCl products like BIHOCL PureCleanse are unique in thier combination of being highly effective while remaining extremely safe. However, before using BIHOCL PureCleanse it's important to clean the wound and surrounding area thoroughly to remove any dirt or debris. The solution should only be applied using a sterile cotton swab or gauze to prevent the introduction of new or additional bacteria into the wound.
If the wound is dressed, the dressing should be removed before applying the solution. If the wound is painful, it may be helpful to numb the area with a local anesthetic before applying the solution.
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References
Sibbald RG, Williamson D, Orsted HL, et al (2000) Preparing the wound bed: debridement, bacterial balance and moisture balance. Ostomy Wound Manag 46: 14–35
Sibbald RG, Orsted HL, Schultz G, Coutts RN, Keast MD (2003) Preparing the wound bed: focus on infection and inflammation. Ostomy Wound Manag 47: 38–43
Bee, T., et al. (2009). Wound bed preparation – cleansing techniques and solutions: A systematic review. Singapore Nursing Journal, 36(1), 16-22.
Atiyeh, B., et al. (2009). Wound cleansing, topical antiseptics and wound healing. International Wound Journal, 6(6), 420-430.
Williams J, Rasmussen E, Robins L, Varela C, Terry D, Harding, K (forward), The Handbook of HOCl, 2021
Sterasure Inc. data on file, 2022
Andrew M. Jenner AM, Emilio Ruiz J, Dunster C, Halliwell B, Mann GE, and Siow RCM. Vitamin C Protects against hypochlorous acid–induced glutathione depletion and DNA base and protein
Winterbourn CC, Brennan SO. Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid. Biochem J. 1997 Aug 15; 326 (Pt 1):87-92.
Li JX, Pang YZ, Tang CS, Li ZQ. Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver. World J Gastroenterol. 2004;10(5):694-698.
Kearns S, Dawson R Jr. Cytoprotective effect of taurine against hypochlorous acid toxicity to PC12 cells. Adv Exp Med Biol. 2000;483:563-70.
Attinger, C and Wolcott, R, Clinically Addressing Biofilm in Chronic Wounds, Adv in Wound Care, Vol 1, No 3, 2012
Robson MC. Treating chronic wounds with hypochlorous acid disrupts biofilm. Wound Prevention and Management 2020;66 (5):9-10.
Day A, Alkhalil A, Carney BC, Hoffman HN, Moffatt LT, Shupp JW. Disruption of Biofilms and Neutralization of Bacteria Using Hypochlorous Acid Solution: An In Vivo and In Vitro Evaluation. Adv Skin Wound Care 2017 Dec;30(12):543-551.
Ragab, I, Kamal, A, The Effectiveness of Hypochlorous Acid Solution on Healing of Infected Diabetic Foot Ulcers, Journal of Education and Practice, 2017, Vol 8, No 8, pg 58-71