From History to High-Tech: How PureGel™ is Transforming Modern Wound Care

Let's journey through wound care history, from ancient remedies to modern technology. In this article we'll discuss how Biomiq’s hypochlorous acid nano-hydrogel—PureGel™—is poised to revolutionize modern approaches to wound care and wound dressing protocols, through superior hydration and biofilm-disrupting properties.

 

Wound care is as old as humanity itself.

Since the earliest civilizations, humans have sought ways to heal wounds, prevent infections, and reduce scarring¹. From early bandages made of honey and cloth to the advent of antibiotics, every era has brought new innovations¹. Today, we stand at the an important inflection point in wound care technology available to Canadian health care professionals, with Biomiq’s recently launched super-oxidizing nano-hydrogel technology: PureGel™.

In this article, we'll explore the fascinating journey of wound care through the ages and examine how modern technologies like PureGel™ are building upon centuries of medical knowledge to offer unprecedented healing capabilities. Understanding this evolution helps us appreciate the significant advantages that today's innovations like PureGel™ bring to patient care and, ultimately, patient outcomes.

Nightingale carved into wood.

A Brief History of Innovation in Wound Care

The evolution of wound care spans thousands of years, shaped by discoveries, medical advancements, and new technologies¹:

  • Ancient Egypt (c. 2600 BC–1500 BC): Egyptian physicians documented treatments using honey, grease, and lint to clean wounds and prevent infection. The Ebers Papyrus (c. 1500 BC) contains the earliest recorded instructions for hemostasis, including cauterization techniques.
  • Ancient Greece and Rome (c. 400 BC–500 AD): Greek and Roman physicians like Hippocrates and Galen introduced the practice of wound drainage, early surgical instruments, and bandaging techniques that included the use of herbal antiseptics.
  • Middle Ages (c. 500 AD–1500 AD): Wound care regressed with the decline of scientific knowledge, often relying on potions and superstitions. However, battlefield injuries led to the necessity of more practical approaches, including early forms of debridement.
  • Renaissance and Early Modern Period (1500s–1800s): The development of antiseptic techniques began with Ambroise Paré’s introduction of ligature over cauterization in the 1500s. Joseph Lister pioneered antiseptic surgery in the 1860s, revolutionizing wound management.
  • 20th Century (1900s–1990s): The discovery of antibiotics, such as penicillin, transformed infection control. The introduction of sterile dressings, synthetic materials, and aqueous hydrogels further improved wound care outcomes.
  • 21st Century (2000s–Present): Today, the rise of bioengineered dressings, nanotechnology, and smart bandages has introduced active healing methods that support cellular repair, reduce infection, and enhance recovery.

Introducing PureGel™: A Leap into the Future

Wound care has seen many groundbreaking advancements, but the emergence of super-oxidizing nano-hydrogel technology marks a new era. PureGel™ stands at the forefront of this innovation, designed to not only protect wounds but actively aid in optimizing their natural healing process.

So, what makes PureGel™ so impactful as a new innovation for Canadian health care?

Three bottles of PureGel nano-hydrogel for skin and wound care.

What is PureGel™?

PureGel™ is a super-oxidizing nano-hydrogel designed to advance modern wound care and patient outcomes by eliminating biofilm, promoting the occlusion of wounds, and promoting optimal wound hygiene to support healthy, healing tissue.

Unlike traditional hydrogels, PureGel™ provides an optimized wound-healing environment while actively combating bacteria and biofilms. Its non-toxic and biocompatible formula makes it suitable for a wide range of wound types, ensuring safe and effective treatment for patients.

  1. Effectiveness Against Biofilm: PureGel™ is scientifically proven to kill up to 99.99999% of biofilm bacteria using the properties of hypochlorous acid (HOCl)², providing comprehensive effectiveness beyond alternative gels.
  2. Formulated for extended delivery of HOCl – Naturally, the viscosity of PureGel™ allows the solution to exist in place on the wound for much longer periods of time when compared to a liquid cleansing solution.Advanced Hydration: Unlike traditional hydrogels, PureGel™ ensures optimal moisture balance, creating an ideal healing environment for wounds.
  3. Super-Oxidizing Power: This nano-hydrogel technology harnesses the power of oxidation caused by hypochlorous acid (HOCl) which is known to combat bacteria and biofilm, reducing infection risks more effectively than conventional antiseptics.
  4. Non-Toxic and Biocompatible: Many antiseptics can cause irritation or damage healthy cells. PureGel™ is designed for safe and painless application, making it suitable for even the most sensitive wounds.

How to Use PureGel™

  1. Prepare the Wound: Before applying PureGel™, cleanse the wound area thoroughly using an appropriate wound-cleaning solution (such as PureCleanse™ hypochlorous acid wound solutoon) to remove debris and bacteria.
  2. Apply PureGel™: Dispense an appropriate amount of gel directly onto the wound, ensuring even coverage over the affected area.
  3. Dress the Wound: Depending on the wound type, the area may be covered with a sterile, non-adherent or occlusive dressing to maintain a hydrated healing environment.
  4. Monitor and Reapply: Reapply PureGel™ with each dressing change, typically once or twice daily, or as directed by facility protocol(s).
  5. Assess Healing Progress: Regularly monitor the wound for signs of healing or infection, adjusting the treatment approach as needed.

How does PureGel™ Compare to Alternatives?

PureGel™ stands out among other wound care products by offering a unique combination of features that surpass traditional hydrogels, antimicrobial gels, collagen gels, alginate gels, and hydrofiber gels.

Unlike many alternatives, PureGel™:

  • Is non-cytotoxic and doesn’t require rinsing – Ensuring that it is safe for healthy tissues while still actively combating infection.
  • Is safe for mucosal tissue – Making it a versatile option for various wound types, including those in sensitive areas.
  • Donates moisture – Maintaining an optimal healing environment similar to traditional hydrogels, but with the added benefits of HOCl.

An Impactful Innovation for Healthcare Professionals and Their Patients

For patients, PureGel™ represents a new standard in wound care, offering faster recovery, less discomfort, and superior protection against infection. For healthcare professionals, it provides a next-generation solution that aligns with modern evidence-based practices in wound management.

From early antiseptic treatments to today's sophisticated nano-hydrogels, the story of wound care is one of constant innovation. PureGel™ is not just another step forward—it is a paradigm shift in how we approach healing. As we continue to push the boundaries of medical science, one thing is certain: the future of wound care is here, and it’s brighter than ever.

References

  1. George Broughton, I. I., Janis, J. E., & Attinger, C. E. (2006). A brief history of wound care. *Plastic and reconstructive surgery*, *117*(7S), 6S-11S.
  2. Nedelea, A.-G., Plant, R. L., Robins, L. I., & Maddocks, S. E. (2021). Testing the efficacy of topical antimicrobial treatments using a two- and five-species chronic wound biofilm model. Journal of Applied Microbiology, 00, 1–10. https://doi.org/10.1111/jam.15239

Related products

PureGel™

A pure, stable hypochlorous acid (HOCl) formulation in the form of an isotonic hydrogel for skin, wounds and burns. Provides extended delivery over time and disrupts biofilm.

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